Cytokine concentrations in the cerebrospinal fluid of Great Danes with cervical spondylomyelopathy. Journal of Veterinary Internal Medicine (2014)
Informações do Resumo
Disponível em: Inglês.
Total de Páginas: 8.
Chronic inflammation is involved in the pathogenesis of human cervical spondylotic myelopathy andcould also play a role in cervical spondylomyelopathy (CSM) in dogs.
Hypothesis/Objectives: That cerebrospinal fluid (CSF) cytokine concentrations would differ between clinically normal(control) and CSM-affected Great Danes (GDs), with affected GDs showing higher levels of inflammatory cytokines, suchas interleukin (IL)-6 and monocyte chemoattractant protein-1/chemokine ligand 2 (MCP-1/CCL2).
Animals: Client-owned GDs: 15 control, 15 CSM-affected