Proteomic analysis of cerebrospinal fluid in canine cervical spondylomyelopathy (2015)

Martin-Vaquero P, da Costa RC, Moore SA, Allen MJ, Green E. Proteomic analysis of cerebrospinal fluid in canine cervical spondylomyelopathy. Spine 40, n. 9, p. 601-612, 2015. (Spine is top journal in human spine field)

Paula Martin-Vaquero , DVM, PhD, Dipl. ACVIM (Neurology), * Ronaldo C. da Costa , DMV, PhD, Dipl. ACVIM (Neurology) ,* Matthew J. Allen , Vet MB, PhD ,* Sarah A. Moore , DVM, Dipl. ACVIM (Neurology), * Jeremy K. Keirsey , MS, † and Kari B. Green , PhD ‡

Informações do Resumo

Disponível em: Inglês.
Total de Páginas: 12.

Study Design. Prospective study.
Objective. To identify proteins with differential expression in the cerebrospinal fl uid (CSF) from 15 clinically normal (control) dogs and 15 dogs with cervical spondylomyelopathy (CSM).
Summary of Background Data. Canine CSM is a spontaneous, chronic, compressive cervical myelopathy similar to human cervical spondylotic myelopathy. There is a limited knowledge of the molecular mechanisms underlying these conditions. Differentially expressed CSF proteins may contribute with novel information about the disease pathogenesis in both dogs and humans.


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